Effectiveness of nicotine patches in relation to genotype in women versus men: randomised controlled trial.
نویسندگان
چکیده
The overall effectiveness of nicotine replacement therapy could be greater if the therapy were targeted at those most likely to respond. Variants of the dopamine D2 receptor (DRD2 32806 C/T) have been implicated in the initiation and maintenance of smoking, 2 and these variants may also be related to response to nicotine replacement therapy. Additionally, mechanisms of nicotine addiction may differ in men and women. With this evidence in mind, we examined whether the response to nicotine replacement therapy is modified by sex and genotype.
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عنوان ژورنال:
- BMJ
دوره 328 7446 شماره
صفحات -
تاریخ انتشار 2004